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Published research

Big questions.
Clearer answers.

17.6–25.0%

Mean weight reduction across TRIUMPH-1 dose groups at 80 weeks.

Research illustration. Group averages are not personal predictions or evidence about retail vials. Read the study.

A useful little tool

Less guesswork.
Clearer calculations.

Convert the quantities you enter into concentration and sample volume.

Open peptide calculator

Start with a good question

Research that’s
easier to navigate.

See the study, its limits, and the next question worth asking.

Feel Healthier

Test what your body’s
been telling you.

Explore an independent health-check service, or learn what common biomarkers measure.

Get a health check

Provided by a separate company. Review its service details and terms.

Know what’s
being measured.

Different markers answer different questions. A result needs its own context.

Look at
the bigger picture.

One measurement is a moment. A qualified clinician can help interpret the pattern.

Connect
the science.

Learn how biomarkers, study findings, and individual health questions fit together.

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to your health check.

Keep your history and priorities in view when speaking with your healthcare professional.

Keep learning

Explore public education.

These educators are not affiliated with PeptideSerum. They do not provide care through this page or endorse our products.

Board-certified urologist · Public educator

Dr. Alex Tatem, MD

His public primer explains peptide categories, evidence differences, and the role of medical oversight. Featured above: his guest interview on Down to Health.

Read his peptide primer Watch on YouTube ↗

A little more context

Keep the evidence in perspective.

What do the weight-research numbers mean?

TRIUMPH-1 studied 2,339 adults without diabetes for 80 weeks. Average weight change was −17.6%, −23.7%, and −25.0% in the assigned 4, 9, and 12 mg groups, versus −3.9% with placebo, using the treatment-regimen analysis. These are different groups’ averages, not an individual response range or a dosing recommendation. Published September 29, 2026 in NEJM.

Earlier 19.0–28.3% headlines used a different analysis. Lilly’s release explains both analyses.

What can self-reported experiences tell us?

Selected public-post summaries can help identify questions for further research. They cannot establish a typical result, cause, time to goal, or side-effect risk.

24 accountsSelected week-worded intervals

About 3.1 lb/week average reported scale-weight change.

29 accountsSeparate longer intervals

About 1.7 lb/week using approximate month/year durations.

Exploratory, unreviewed self-report summaries. These selected groups include uncertain exposure, other treatments, lifestyle changes, and assumptions about timing. No independent human source review is complete. They are kept separate from clinical trial data and never used in this page’s weight illustration.

Is this medical care?

No. PeptideSerum provides research products and education. This page does not diagnose, prescribe, choose a dose, or establish a clinician–patient relationship. Retatrutide is investigational. Read Lilly’s current research information.

Which price will I pay?

Product prices follow your current store membership status. Logged-in paid PRO members receive member pricing; other accounts receive public pricing. Product previews refresh from the current catalog before you add anything to your cart.

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Research checked October 12, 2026. Study findings concern the medicines and participants studied; they do not establish outcomes from PeptideSerum research products.

Educator identities and public resources: Dr. Froese’s official education site · Dr. Tatem’s practice profile. External sites set their own terms, services, and commercial relationships.

Peptide Serum

A clearer starting point

You’re on your way to feeling your best.

Start with a clearer picture of your hormone levels, testing, and questions to discuss with a qualified healthcare professional.

Health checks are provided by an independent service. PeptideSerum research products are not treatments.

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Choose the research question you want to understand first.

Choose one option

Your choices help organize this research page. They are not a medical assessment.

Your answers stay in this window and clear when you close it.

An illustration of published research

Put the study averages
in perspective.

Move the slider to see what the trial-group averages represent at a selected starting weight.

Illustrated weight change at 80 weeksIllustration of 35.2 to 50.0 pounds of weight change, based on different trial-group averages.17.6–25.0% across different trial groups

Group averages are not a personal prediction. TRIUMPH-1 studied 2,339 adults without diabetes over 80 weeks. This illustration does not establish eligibility, a suitable dose, or outcomes from retail research vials.

Read the study details

The published treatment-regimen analysis reported average body-weight changes of −17.6%, −23.7%, and −25.0% in the 4, 9, and 12 mg groups, versus −3.9% with placebo. The study medicine was administered under clinical supervision. Gastrointestinal adverse events were most common. Retatrutide remains investigational.

Read TRIUMPH-1 in NEJM ↗

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For personal health or treatment decisions, speak with your own qualified healthcare professional.

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